Delivery platform

particules

More than thirty active ingredients have already been formulated and an algorithm has been designed to rapidly identify the physicochemical formulation conditions. Once optimized, the formulations are controlled for long storage stability; the specifications can be variable depending on the use, for one week up to one year.

This formulation offers a protection of the drug, and allows a cell-targeted delivery due to the particular shape of the vector, thus decreasing the amount of drug administrated and by consequence the potential toxicity of this drug.

  • Active Pharmaceutical Ingredient Delivery System
    (Immunomodulators, Antibiotics, Antiviral, Anticancer, etc)
  • Imaging System

 

Active Pharmaceutical Ingredient Delivery System
(Immunomodulators, Antibiotics, Antiviral, Anticancer, etc)

  •        TLR / Nod agonists

TLR, Nod agonists are potent inducers of innate immune system, and have been evaluated as potential adjuvants, or in context of carcinogenesis with high therapeutic potential. However, due to their pro-inflammatory properties, their systemic delivery is often associated with serious adverse effects.

Check-out the available proinflammatory i-Particles !

Nod 1/2 agonist-containing i-Particles: here or here
TLR agonist-containing i-Particles available, please contact Adjuvatis for an updated list
And customized i-Particles with your ligand

Please contact Adjuvatis contact[at]adjuvatis.com for an individualized inquiry.

 

  • Hydrophobic drugs

Poor water solubility is the most significant barrier limiting drug development. Adjuvatis offers to solubilize your highly hydrophobic API by their encapsulation onto the i-Particles. Thanks to our production process, without any surfactant nor residual solvent, and the use of a biodegradable polymer FDA approved, this delivery system has a high potential in clinical development.

Please contact Adjuvatis contact[at]adjuvatis.com for an individualized inquiry.

 

Imaging System

Adjuvatis proposes particles for imaging by Microscopy / Live-tomography (Near Infra-red i-Particles) / Micron Electronic Microscopy / Correlative Microscopy

fluorescent-i-particles

The co-encapsulation with you API allows the co-evaluation of the fate of the particles and therapeutic efficacy.

gold-particles

Our new OFFER: i-Particles suitable for Transmission Electron Microscopy by encapsulation of gold nanoparticles, also suitable with a co-encapsulation of a fluorophore for observations by correlative microscopy

 

 

 

 

 

Adjuvatis-i-Particles-Fluo2

Please contact us at: contact[at]adjuvatis.com for further information or to request a quotation